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Product details

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL

Catalog number BNC402754-500

Price for BNC402754-500

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Size / count 1x 500 µL

About this product

Recognizes a protein of 140 kDa, which is identified as the complement receptor 2 (CR2) or CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC402754-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD21; Complement C3d receptor (C3DR) ; Complement Receptor type 2 (CR2) ; CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CR2
Gene ID
1380
NCBI Gene ID
445757
UniProt
P20023
Swiss Prot
P20023
Host
Mouse
Species Reactivity
Human
Reactivity
CD21
Immunogen
Recombinant fragment (around aa 142-240) of human CR2 (CD21) protein (exact sequence is proprietary)
Target Antigen
CD21
Clonality
Monoclonal
Clone
CR2/2754
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
MOLT4, Raji or WEHI-231 cells. Tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
140 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL?

The catalog number for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL is BNC402754-500.

What sizes are available for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL in stock?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL?

The safety data sheet for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/2754), CF640R conjugate, 0.1mg/mL used for?

Recognizes a protein of 140 kDa, which is identified as the complement receptor 2 (CR2) or CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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