Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL

Catalog number BNC472781-500

Price for BNC472781-500

Size / count 1x 500 µL

About this product

Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively) . Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472781-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cathepsin D; CTSD; Lysosomal aspartyl peptidase
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CTSD
Gene ID: 1509
NCBI Gene ID: 654447
UniProt: P07339
Swiss Prot: P07339
Host: Mouse
Species Reactivity: Human
Reactivity: Cathepsin D
Immunogen: Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary)
Target Antigen: Cathepsin D
Clonality: Monoclonal
Clone: CTSD/2781
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: K-562, A431 or SK-BR3 cells. Kidney, Liver, Lung or Breast.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 46 kDa (Procathepsin D) ; 28 kDa (Cathepsin D)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL?

The catalog number for Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL is BNC472781-500.

What sizes are available for Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL in stock?

Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02aa061270361e107311/msds/bnc472781-500.pdf.

What is Cathepsin D (Tumor Marker) (CTSD/2781), CF647 conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.