Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2781-500

Price for BNCB2781-500

Size / count 1x 500 µL

About this product

Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively) . Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2781-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cathepsin D; CTSD; Lysosomal aspartyl peptidase
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CTSD
Gene ID: 1509
NCBI Gene ID: 654447
UniProt: P07339
Swiss Prot: P07339
Host: Mouse
Species Reactivity: Human
Reactivity: Cathepsin D
Immunogen: Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary)
Target Antigen: Cathepsin D
Clonality: Monoclonal
Clone: CTSD/2781
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: K-562, A431 or SK-BR3 cells. Kidney, Liver, Lung or Breast.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 46 kDa (Procathepsin D) ; 28 kDa (Cathepsin D)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL?

The catalog number for Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL is BNCB2781-500.

What sizes are available for Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL in stock?

Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e10169b/msds/bncb2781-500.pdf.

What is Cathepsin D (Tumor Marker) (CTSD/2781), Biotin conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.