CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL

Catalog number BNC942789-500

Price for BNC942789-500

Size / count 1x 500 µL

About this product

This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC942789-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Gp55; granulophysin; Lysosomal-associated membrane protein 3 (LAMP-3) ; Mast cell antigen AD1; Melanoma-associated antigen ME491; MLA1; NGA; Ocular melanoma-associated antigen; OMA81H; PTLGP40; Tetraspanin-30; TSPAN30
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD63
Gene ID: 967
NCBI Gene ID: 445570
UniProt: P08962
Swiss Prot: P08962
Host: Mouse
Species Reactivity: Human, Mouse
Reactivity: CD63
Immunogen: Recombinant human CD63 protein fragment (around aa100-197) (exact sequence is proprietary)
Target Antigen: CD63
Clonality: Monoclonal
Clone: LAMP3/2789
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: U87MG, SK-MEL-28, HL60, THP-1, NIH/3T3, or MCF-7 cells. Human melanoma, spleen or lymphoma tissue.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 26 kDa (core protein) ; 30-60 kDa (glycosylated)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL?

The catalog number for CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL is BNC942789-500.

What sizes are available for CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL?

CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL in stock?

CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL?

CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL?

The safety data sheet for CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100c58/msds/bnc942789-500.pdf.

What is CD63 (Late Endosomes Marker) (LAMP3/2789), CF594 conjugate, 0.1mg/mL used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.