Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL

Catalog number BNC042796-100

Price for BNC042796-100

Size / count 1x 100 µL

About this product

Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3) . This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80%) and specificity (100%) in recognizing squamous cell carcinoma (SqCC) . Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042796-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 130kDa pemphigus vulgaris antigen (PVA) ; Balding (Bal) ; Cadherin family member 6 (CDHF6) ; Desmoglein-3 (DSG3)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: DSG3
Gene ID: 1830
NCBI Gene ID: 1925
UniProt: P32926
Swiss Prot: P32926
Host: Mouse
Species Reactivity: Human
Reactivity: Desmoglein-3
Immunogen: Recombinant fragment (around aa 379-491) human DSG3 protein (exact sequence is proprietary)
Target Antigen: Desmoglein-3
Clonality: Monoclonal
Clone: DSG3/2796
Type: Primary
Source: Animal
Origin: Animal
Positive Control: A431 cells. Skin or Lung Squamous Cell Carcinoma (SCC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 130 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL?

The catalog number for Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL is BNC042796-100.

What sizes are available for Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL in stock?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ab061270361e107afe/msds/bnc042796-100.pdf.

What is Desmoglein-3 (Squamous Cell Marker) (DSG3/2796), CF405S conjugate, 0.1mg/mL used for?

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.