MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL

Catalog number BNC472818-100

Price for BNC472818-100

Size / count 1x 100 µL

About this product

This MAb reacts with MUC1. The dominant epitope of this MAb has not yet been determined. MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and over expressed abundantly in 90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four c-erbB receptors and localize with c-erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472818-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Breast carcinoma-associated antigen DF3; CA15-3; H23AG; KL-6; MAM6; Mucin 1 cell surface associated; ; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; Tumor-associated epithelial membrane antigen
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MUC1
Gene ID: 4582
NCBI Gene ID: 89603
UniProt: P15941
Swiss Prot: P15941
Host: Rabbit
Species Reactivity: Human, Mouse
Reactivity: CA15-3|CD227|EMA|MUC1
Immunogen: Human milk-fat globule membranes (HMFGM)
Target Antigen: CA15-3 | CD227 | EMA | MUC1
Clonality: Recombinant Monoclonal
Clone: MUC1/2818R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Mucins
Positive Control: MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 265-400 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL?

The catalog number for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL is BNC472818-100.

What sizes are available for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL in stock?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a4061270361e1052f3/msds/bnc472818-100.pdf.

What is MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2818R), CF647 conjugate, 0.1mg/mL used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.