Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL

Catalog number BNC882827-100

Price for BNC882827-100

Size / count 1x 100 µL

About this product

Cig2 is a cyclin that functions as the catalytic subunit of cyclin-dependent kinases (Cdks) in the fission yeast Schizosaccharomyces pombe. It is a B-type, S phase cyclin that is required for both the G1/S and G2/M cell cycle transitions and is expressed in a sharp spike that peaks during the G1/S period. Cig2 binds to Cdc2 (Cdk), and the resulting Cdc2/Cig2 complex controls the G1/S transition of the cell cycle. Disruption of Cig2 delays the onset of mitosis. The expression of the Cig2 gene is dependent on Mlu1-binding factor (MBF), and the protein is destroyed during anaphase by the APC/cyclosome (APC/C) and Skp1/Cullin-1/F-box (SCF), thereby ensuring the spike expression pattern of Cig2. SCF regulates Cig2 levels in a dual manner, transcriptionally and post-translationally, while APC/C only destroys the protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC882827-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: B type S phase cyclin antibody
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: Not Known
Gene ID: Not Known
NCBI Gene ID: Not Known
UniProt: Not Known
Swiss Prot: Not Known
Host: Mouse
Species Reactivity: Yeast
Reactivity: Cig2
Immunogen: Bacterial S. pombe Cig2 Purified protein.
Target Antigen: Cig2
Clonality: Monoclonal
Clone: 3A11/5
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Red blood cell lysate; Human colon and lung tissue.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~50 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL?

The catalog number for Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL is BNC882827-100.

What sizes are available for Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL?

Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL in stock?

Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL?

Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a4061270361e105387/msds/bnc882827-100.pdf.

What is Cig2 (3A11/5), CF488A conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.