NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL

Catalog number BNUB2836-100

Price for BNUB2836-100

Size / count 1x 100 µL

About this product

NKX3. 1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21. 2, which frequently undergoes a loss of heterozygosity. NKX3. 1 expression is highly restricted in prostate epithelial cells and therefore can be used as a diagnostic biomarker for prostate cancer and other metastatic lesions of prostatic origin. Furthermore, NKX3. 1 shows better sensitivity than Prostate Specific Antigen (PSA) for identifying metastatic prostatic adenocarcinoma. This suggests that immunohistochemical staining of NKX3. 1, along with other prostate-restricted markers, may be valuable for the definitive determination of prostatic origin in poorly differentiated metastatic carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB2836-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: NK3 Homeobox 1; Homeobox Protein NK-3 Homolog A; NKX3-1; NKX3A; NK3 Transcription Factor Related; Locus 1 (Drosophila) ; NK3 Transcription Factor Related; Locus 1; NK Homeobox (Drosophila) ; Family 3; A; NK3 Transcription Factor Homolog A; NK Homeobox; Family 3; A; Homeobox Protein Nkx-3.1; BAPX2; NKX3
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NKX3-1
Gene ID: 4824
NCBI Gene ID: 55999
UniProt: Q99801
Swiss Prot: Q99801
Host: Mouse
Species Reactivity: Human
Reactivity: NKX3.1
Immunogen: Recombinant fragment (around aa 92-224) of human NKX3.1 protein (exact sequence is proprietary)
Target Antigen: NKX3.1
Clonality: Monoclonal
Clone: NKX3.1/2836
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Highly expressed in the prostate and at a lower level in the testis.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 35 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL?

The catalog number for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL is BNUB2836-100.

What sizes are available for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL in stock?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL?

Estimated delivery time for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL?

The safety data sheet for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029f061270361e1033d3/msds/bnub2836-100.pdf.

What is NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2836), 0.2mg/mL used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.