Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL

Catalog number BNC402838-500

Price for BNC402838-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3) . This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80%) and specificity (100%) in recognizing squamous cell carcinoma (SqCC) . Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC402838-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 130kDa pemphigus vulgaris antigen (PVA) ; Balding (Bal) ; Cadherin family member 6 (CDHF6) ; Desmoglein-3 (DSG3)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: DSG3
Gene ID: 1830
NCBI Gene ID: 1925
UniProt: P32926
Swiss Prot: P32926
Host: Mouse
Species Reactivity: Human
Reactivity: Desmoglein-3
Immunogen: Recombinant fragment (around aa 379-491) human DSG3 protein (exact sequence is proprietary)
Target Antigen: Desmoglein-3
Clonality: Monoclonal
Clone: DSG3/2838
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: A431 cells. Skin or Lung Squamous Cell Carcinoma (SCC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 130 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL?

The catalog number for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL is BNC402838-500.

What sizes are available for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL in stock?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029f061270361e1037c0/msds/bnc402838-500.pdf.

What is Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF640R conjugate, 0.1mg/mL used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.