Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL

Catalog number BNC472838-500

Price for BNC472838-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3) . This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80%) and specificity (100%) in recognizing squamous cell carcinoma (SqCC) . Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472838-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 130kDa pemphigus vulgaris antigen (PVA) ; Balding (Bal) ; Cadherin family member 6 (CDHF6) ; Desmoglein-3 (DSG3)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: DSG3
Gene ID: 1830
NCBI Gene ID: 1925
UniProt: P32926
Swiss Prot: P32926
Host: Mouse
Species Reactivity: Human
Reactivity: Desmoglein-3
Immunogen: Recombinant fragment (around aa 379-491) human DSG3 protein (exact sequence is proprietary)
Target Antigen: Desmoglein-3
Clonality: Monoclonal
Clone: DSG3/2838
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: A431 cells. Skin or Lung Squamous Cell Carcinoma (SCC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 130 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL?

The catalog number for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL is BNC472838-500.

What sizes are available for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL in stock?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a9061270361e106ba9/msds/bnc472838-500.pdf.

What is Desmoglein-3 (Squamous Cell Marker) (DSG3/2838), CF647 conjugate, 0.1mg/mL used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.