Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL

Catalog number BNC042839-100

Price for BNC042839-100

Size / count 1x 100 µL

About this product

Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3) . This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80%) and specificity (100%) in recognizing squamous cell carcinoma (SqCC) . Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042839-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 130kDa pemphigus vulgaris antigen (PVA) ; Balding (Bal) ; Cadherin family member 6 (CDHF6) ; Desmoglein-3 (DSG3)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: DSG3
Gene ID: 1830
NCBI Gene ID: 1925
UniProt: P32926
Swiss Prot: P32926
Host: Mouse
Species Reactivity: Human
Reactivity: Desmoglein-3
Immunogen: Recombinant fragment (around aa 379-491) human DSG3 protein (exact sequence is proprietary)
Target Antigen: Desmoglein-3
Clonality: Monoclonal
Clone: DSG3/2839
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: A431 cells. Skin or Lung Squamous Cell Carcinoma (SCC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 130 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL?

The catalog number for Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL is BNC042839-100.

What sizes are available for Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL in stock?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL?

Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b0061270361e1094ac/msds/bnc042839-100.pdf.

What is Desmoglein-3 (Squamous Cell Marker) (DSG3/2839), CF405S conjugate, 0.1mg/mL used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.