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Product details
Catalog number BNUM2842-50
Price for BNUM2842-50
Size / count 1x 50 µL
The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad51. XRCC1 is a protein that facilitates the DNA base excision repair pathway by interacting with DNA ligase III and DNA polymerase to repair DNA single-strand breaks. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair. XRCC4 is an accessory factor of DNA Ligase IV that preferentially binds DNA with nicks or broken ends. XRCC4 binds to DNA Ligase IV and enhances its joining activity, and it is also involved in V (D) J recombination. Any defect in one of the known components of the DNA repair/V (D) J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA Ligase IV) leads to abortion of the V (D) J rearrangement process and early block in both T and B cell maturation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for XRCC3 (10F1/6), 1mg/mL is BNUM2842-50.
XRCC3 (10F1/6), 1mg/mL is available in the following size(s): 1x 50 µL.
XRCC3 (10F1/6), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
XRCC3 (10F1/6), 1mg/mL is manufactured by Biotium.
Estimated delivery time for XRCC3 (10F1/6), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for XRCC3 (10F1/6), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e10196a/msds/bnum2842-50.pdf.
The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad51. XRCC1 is a protein that facilitates the DNA base excision repair
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.
If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.
