CD64 (10.1), CF640R conjugate, 0.1mg/mL

About this product

CD64 is an Fc receptor that plays a putative role in the initiation of cell-mediated cytotoxicity. Thus far, three genes encoding four distinct CD64 transcripts have been described. CD64 has been shown to associate with signal transducing subunit of the high affinity IgE receptor. Src family kinases Hck and Lyn show increased kinase activity and will co-immunoprecipitate with CD64 subsequent to receptor cross linking. CD64 is constitutively expressed on monocytes and macrophages; exposure of granulocytes to cytokines such as IFN-gamma and G-CSF can induce CD64 expression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC402846-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

CD64; CD64A; CD64b; CD64c; Fc fragment of IgG; high affinity Ia; receptor (CD64) ; FCGR1; FCGR1A; FCGR1B; FCGR1C; FcRI; FcRIB; FCRIC; High affinity immunoglobulin gamma Fc receptor IB; IGFR1; IGFRB; IGFRC

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

FCG10.1A

Gene ID

2209

NCBI Gene ID

534956; 77424

UniProt

P12314

Swiss Prot

P12314

Host

Mouse

Species Reactivity

Human

Reactivity

CD64

Immunogen

FCG10.1A / CD64 antibody was raised against rheumatoid synovial fluid cells and fibronectin Purified human monocytes.

Target Antigen

CD64

Clonality

Monoclonal

Clone

10.1

Type

Primary

Source

Animal

Origin

Animal

Applications

Functional studies (published) |Flow, surface (verified) |IF (verified)

Positive Control

Human tonsil.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

43 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Infect Immun (2003) 71: 5871-5880. (functional studies)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF640R