Tal1 (BTL73), CF405S conjugate, 0.1mg/mL

Catalog number BNC042852-500

Price for BNC042852-500

Size / count 1x 500 µL

About this product

Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042852-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BHLHa17; Class A basic helix-loop-helix protein 17; OTTHUMP00000009563; OTTHUMP00000009564; SCL; STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR; Stem cell protein; T cell acute lymphocytic leukemia 1; T cell acute lymphocytic leukemia 1 protein; T cell acute lymphocytic leukemia 1 protein; T cell leukemia/lymphoma 5 protein; T-cell acute lymphocytic leukemia protein 1; T-cell leukemia/lymphoma protein 5; Tal 1 product; TAL 1 protein; TAL bHLH transcription factor 1 erythroid differentiation factor; TAL-1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TAL1
Gene ID: 6886
NCBI Gene ID: 705618
UniProt: P17542
Swiss Prot: P17542
Host: Mouse
Species Reactivity: Human
Reactivity: Tal1
Immunogen: Recombinant human full-length TAL1 protein
Target Antigen: Tal1
Clonality: Monoclonal
Clone: BTL73
Type: Primary
Source: Animal
Origin: Animal
Applications: CHiP (published) |Flow, intracellular (published) |IHC (published) |IHC, FFPE (published) |EMSA (published)
Positive Control: A549 xenograft.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 42 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. EMBO J (1997) 16:3145-3157. (WB) Br J Haematol (1998) 102: 449-457. (Flow; IHC) Blood (2002) 100(2): 491-500. (WB; IHC, FFPE; EMSA) Oncogene (2011) 30: 1252-1260. (CHiP)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Tal1 (BTL73), CF405S conjugate, 0.1mg/mL?

The catalog number for Tal1 (BTL73), CF405S conjugate, 0.1mg/mL is BNC042852-500.

What sizes are available for Tal1 (BTL73), CF405S conjugate, 0.1mg/mL?

Tal1 (BTL73), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Tal1 (BTL73), CF405S conjugate, 0.1mg/mL in stock?

Tal1 (BTL73), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tal1 (BTL73), CF405S conjugate, 0.1mg/mL?

Tal1 (BTL73), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Tal1 (BTL73), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Tal1 (BTL73), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Tal1 (BTL73), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Tal1 (BTL73), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029e061270361e102df7/msds/bnc042852-500.pdf.

What is Tal1 (BTL73), CF405S conjugate, 0.1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.