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Product details

CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL

Catalog number BNC402853-500

Price for BNC402853-500

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Size / count 1x 500 µL

About this product

Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) . It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1) . This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC402853-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM-1; Intercellular adhesion molecule 1; Ly 47; Major group rhinovirus receptor; MALA2; MyD10; Surface antigen of activated B cells
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ICAM1
Gene ID
3383
NCBI Gene ID
643447
UniProt
P05362
Swiss Prot
P05362
Host
Mouse
Species Reactivity
Human, Pig
Reactivity
CD54|ICAM-1
Immunogen
Human monocytes.
Target Antigen
CD54 | ICAM-1
Clonality
Monoclonal
Clone
15.2
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published) |IF (published) |IHC, frozen (published)
Field of Research
Immunology
Positive Control
Raji cells, MOLT 4, HeLa or SW480 cells. Human tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
85-115 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Leukocyte Biol (1998) 64: 519. (Flow, surface) Inv Ophthalmol Visual Sci (2003) 44: 1888-1896. (IHC, frozen) Blood (1999) 93(11): 3723-3735. (IF) J Cell Biol (1992) 116(6): 1527-1535. (functional studies)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL?

The catalog number for CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL is BNC402853-500.

What sizes are available for CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL?

CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL in stock?

CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL?

CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL?

The safety data sheet for CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100bf7/msds/bnc402853-500.pdf.

What is CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL used for?

Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) . It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of othe

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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