CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2853-100

Price for BNCB2853-100

Size / count 1x 100 µL

About this product

Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) . It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1) . This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2853-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM-1; Intercellular adhesion molecule 1; Ly 47; Major group rhinovirus receptor; MALA2; MyD10; Surface antigen of activated B cells
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ICAM1
Gene ID: 3383
NCBI Gene ID: 643447
UniProt: P05362
Swiss Prot: P05362
Host: Mouse
Species Reactivity: Human, Pig
Reactivity: CD54|ICAM-1
Immunogen: Human monocytes.
Target Antigen: CD54 | ICAM-1
Clonality: Monoclonal
Clone: 15.2
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |Functional studies (published) |IF (published) |IHC, frozen (published)
Field of Research: Immunology
Positive Control: Raji cells, MOLT 4, HeLa or SW480 cells. Human tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 85-115 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Leukocyte Biol (1998) 64: 519. (Flow, surface) Inv Ophthalmol Visual Sci (2003) 44: 1888-1896. (IHC, frozen) Blood (1999) 93(11): 3723-3735. (IF) J Cell Biol (1992) 116(6): 1527-1535. (functional studies)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL?

The catalog number for CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL is BNCB2853-100.

What sizes are available for CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL?

CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL in stock?

CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL?

CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e1003eb/msds/bncb2853-100.pdf.

What is CD54 / ICAM-1 (15.2), Biotin conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.