HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL

Catalog number BNC472866-500

Price for BNC472866-500

Size / count 1x 500 µL

About this product

Recognizes a DQ antigen, which is a dimer of 60 kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages) . The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. This MAb strongly blocks cytotoxicity activity of T4-positive cytotoxic T cell clones. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472866-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CELIAC1; DC 4 alpha chain Gluten sensitive enteropathy (celiac disease) (GSE) ; HLA class II histocompatibility antigen DQ (1) alpha chain; HLA class II histocompatibility antigen DQ (3) alpha chain; HLA DQA1; HLA DQB1; IDDM1; Leucocyte antigen DQA1; Major histocompatibility complex class II DQ alpha 1; Major histocompatibility complex class II DQ beta 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: HLA-DQ
Gene ID: 3117; 3118; 3119
NCBI Gene ID: 550475
UniProt: P01908; P01909; P01920
Swiss Prot: P01908; P01909; P01920
Host: Rabbit
Species Reactivity: Human, Pig
Reactivity: HLA-DQ
Immunogen: Recombinant full-length human HLA-DQ protein
Target Antigen: HLA-DQ
Clonality: Recombinant Monoclonal
Clone: HLA-DQA1/2866R
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified)
Positive Control: Raji cells. Tonsil or lymph node
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 60 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL?

The catalog number for HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL is BNC472866-500.

What sizes are available for HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL?

HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL in stock?

HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL?

HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02aa061270361e107434/msds/bnc472866-500.pdf.

What is HLA-DQ (MHC II) (HLA-DQA1/2866R), CF647 conjugate, 0.1mg/mL used for?

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.