• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL

Catalog number BNUM2877-50

Price for BNUM2877-50

Sign In for Pricing

Size / count 1x 50 µL

About this product

CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out) . The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM2877-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
B220, CD45R, GP180, Leukocyte common antigen (LCA), Loc, Ly-5, Lyt-4, Protein tyrosine phosphatase receptor type C (PTPRC), Receptor-type tyrosine-protein phosphatase C, T200 glycoprotein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PTPRC
Gene ID
5788
NCBI Gene ID
654514
UniProt
P08575
Swiss Prot
P08575
Host
Rabbit
Species Reactivity
Human
Reactivity
CD45RB
Immunogen
Recombinant full-length human PTPRC protein
Target Antigen
CD45RB
Clonality
Recombinant Monoclonal
Clone
PTPRC/2877R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Immunology, Signal transduction
Positive Control
Raji, Ramos, U-698, or GA-10 cells. Tonsil
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
180-220 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL?

The catalog number for CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL is BNUM2877-50.

What sizes are available for CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL?

CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL in stock?

CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL?

CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL?

Estimated delivery time for CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL?

The safety data sheet for CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100df7/msds/bnum2877-50.pdf.

What is CD45RB (B-Cell Marker) (PTPRC/2877R), 1mg/mL used for?

CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5,

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

You Might Also Like
CD4 (EDU-2), CF405S conjugate, 0.1mg/mL
CD4 (EDU-2), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040345-100
CD3e (CRIS-7), CF640R conjugate, 0.1mg/mL
CD3e (CRIS-7), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC401050-500
CD63 (MX-49.129.5), CF405S conjugate, 0.1mg/mL
CD63 (MX-49.129.5), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040525-500
CD54 / ICAM-1 (15.2), CF568 conjugate, 0.1mg/mL
CD54 / ICAM-1 (15.2), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC682853-500
HLA-Aw32 & HLA-A25 (MHC I) (CATA-1), CF647 conjugate, 0.1mg/mL
HLA-Aw32 & HLA-A25 (MHC I) (CATA-1), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471073-100
TGF-beta (1D11.16.8), CF568 conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680977-100
CD3e (B-B12), CF647 conjugate, 0.1mg/mL
CD3e (B-B12), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471052-500
CD106 / VCAM1 (B-K9), CF594 conjugate, 0.1mg/mL
CD106 / VCAM1 (B-K9), CF594 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC940304-100