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Product details

Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL

Catalog number BNC042879-500

Price for BNC042879-500

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Size / count 1x 500 µL

About this product

Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2) ; and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer's disease and Down syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC042879-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Developmentally regulated brain protein; Drebrin 1; Drebrin; Drebrin E; Drebrin E2; Drebrin1; DrebrinE
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
DBN1
Gene ID
1627
NCBI Gene ID
130316
UniProt
Q16643
Swiss Prot
Q16643
Host
Mouse
Species Reactivity
Human
Reactivity
Drebrin 1
Immunogen
Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
Target Antigen
Drebrin 1
Clonality
Monoclonal
Clone
DBN1/2879
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
120 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL?

The catalog number for Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL is BNC042879-500.

What sizes are available for Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL?

Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL in stock?

Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL?

Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a4061270361e1053b7/msds/bnc042879-500.pdf.

What is Drebrin 1 (DBN1) (DBN1/2879), CF405S conjugate, 0.1mg/mL used for?

Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2) ; and an adult type (A), generated by

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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