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Product details

Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL

Catalog number BNC882891-100

Price for BNC882891-100

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Size / count 1x 100 µL

About this product

The complement component proteins, C2, C3, C4 and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors, C3aR, C1R and C5aR, induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation and cellular chemotaxis. C3d is a terminal degradation product of C3 that plays an important role in modulation of the adaptive immune response through the interaction with complement receptor type 2 (CR2) . CR2 is important in the switched-isotype, high-affinity and memory humoral immune responses to T-dependent foreign antigens, as well as in the development of the natural antibody repertoire. This pH- and ionic strength-dependent association of C3d with CR2 represents a link between innate and adaptive immunity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC882891-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Acylation stimulating protein cleavage product; AHUS5; ARMD9; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement component C3; CPAMD1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
C3
Gene ID
718
NCBI Gene ID
529053
UniProt
P01024
Swiss Prot
P01024
Host
Mouse
Species Reactivity
Human
Reactivity
Complement 3d
Immunogen
Recombinant full-length human Complement C3 protein
Target Antigen
Complement 3d
Clonality
Monoclonal
Clone
C3D/2891
Type
Primary
Source
Animal
Origin
Animal
Positive Control
Human kidney or rejected renal transplant tissue.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
35 kDa (predicted)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL?

The catalog number for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL is BNC882891-100.

What sizes are available for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL?

Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL in stock?

Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL?

Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e105018/msds/bnc882891-100.pdf.

What is Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF488A conjugate, 0.1mg/mL used for?

The complement component proteins, C2, C3, C4 and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors, C3aR, C1R and C5aR, induces proinflammatory events, such as cellular degranulation, smooth muscle

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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