CD29 (Stem Cell Marker) (12G10), CF405S conjugate, 0.1mg/mL

About this product

Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC042905-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

Fibrinogen Receptor beta subunit; FNRB; Glycoprotein IIa (GPIIA) ; Integrin beta-1 (ITGB1) ; integrin VLA-4 beta subunit; MDF2; MSK12; Very Late Activation Protein beta Polypeptide; VLA-4 subunit beta; VLA-BETA; VLAB

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ITGB1

Gene ID

3688

NCBI Gene ID

643813

UniProt

P05556

Swiss Prot

P05556

Host

Mouse

Species Reactivity

Human

Reactivity

CD29

Immunogen

Purified human beta 1 integrin from HT1080 fibrosarcoma cell extract.

Target Antigen

CD29

Clonality

Monoclonal

Clone

12G10

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, surface (published) |Functional studies (published) |IF (published) |IP (published)

Positive Control

HT1080 whole cell lysate. HeLa cell line.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

110 kDa (non-reduced) & 130 kDa (reduced)

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. FEBS Lett (1995) 363: 118-122. (functional studies) J Cell Sci (2005) 118: 4009-4016. (IP) Traffic (2012) 13: 610-625. (Flow, IF)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF405S