Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL

Catalog number BNC042911-100

Price for BNC042911-100

Size / count 1x 100 µL

About this product

Nestin is a major intermediate filament (IF) protein of embryonic central nervous system progenitor cells. It is also a component of the dynamic IF network during muscle development, where it polymerizes with Desmin and Vimentin. Nestin co-assembles with Vimentin or -internexin and forms heterodimer coiled-coil molecules which then further assemble into 10 nml IFs. Deletion of the IF consensus rod domain in nestin alters nestin localization in CNS precursor cells and radial glial cells in vivo. Nestin is a marker for neuroepithelial stem cells, glioma cells and tumor endothelial cells during rapid growth. During axon elongation of differentiation neurons, nestin localizes to the growth cones and may play a role in growth cone guidance. In the rat adrenal gland, nestin is expressed by the zona fasciculata and the zona reticularis. Nestin is also expressed by dermatomal cells and by myoblasts during the earliest stages of myogenesis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042911-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ESTM 46; FLJ21841; Intermediate filament protein; Nbla00170; nes
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NES
Gene ID: 10763
NCBI Gene ID: 527971
UniProt: P48681
Swiss Prot: P48681
Host: Mouse
Species Reactivity: Human
Reactivity: Nestin
Immunogen: Recombinant human NES protein fragment around aa 698-844 (exact sequence is proprietary)
Target Antigen: Nestin
Clonality: Monoclonal
Clone: NES/2911
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human kidney, ovary, cervix, breast, colon, endometrium, cerebellum, lung, prostate, skin and human melanoma tissue. HeLa cell lysate. SH-SY5Y cells.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 190-200 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL?

The catalog number for Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL is BNC042911-100.

What sizes are available for Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL?

Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL in stock?

Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL?

Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e1001a1/msds/bnc042911-100.pdf.

What is Nestin (Cancer Stem Cell Marker) (NES/2911), CF405S conjugate, 0.1mg/mL used for?

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.