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Product details
Catalog number BNC472911-500
Price for BNC472911-500
Size / count 1x 500 µL
Nestin is a major intermediate filament (IF) protein of embryonic central nervous system progenitor cells. It is also a component of the dynamic IF network during muscle development, where it polymerizes with Desmin and Vimentin. Nestin co-assembles with Vimentin or -internexin and forms heterodimer coiled-coil molecules which then further assemble into 10 nml IFs. Deletion of the IF consensus rod domain in nestin alters nestin localization in CNS precursor cells and radial glial cells in vivo. Nestin is a marker for neuroepithelial stem cells, glioma cells and tumor endothelial cells during rapid growth. During axon elongation of differentiation neurons, nestin localizes to the growth cones and may play a role in growth cone guidance. In the rat adrenal gland, nestin is expressed by the zona fasciculata and the zona reticularis. Nestin is also expressed by dermatomal cells and by myoblasts during the earliest stages of myogenesis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Nestin (Cancer Stem Cell Marker) (NES/2911), CF647 conjugate, 0.1mg/mL is BNC472911-500.
Nestin (Cancer Stem Cell Marker) (NES/2911), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
Nestin (Cancer Stem Cell Marker) (NES/2911), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Nestin (Cancer Stem Cell Marker) (NES/2911), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Nestin (Cancer Stem Cell Marker) (NES/2911), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Nestin (Cancer Stem Cell Marker) (NES/2911), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ad061270361e1081e4/msds/bnc472911-500.pdf.
Nestin is a major intermediate filament (IF) protein of embryonic central nervous system progenitor cells. It is also a component of the dynamic IF network during muscle development, where it polymerizes with Desmin and Vimentin. Nestin co-assembles with Vimentin or -internexin and forms heterodimer
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
