MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL

Catalog number BNUB2927-100

Price for BNUB2927-100

Size / count 1x 100 µL

About this product

The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is an MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB2927-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: DNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTBP; GTMBP; hMSH6; HNPCC5; HSAP; MSH6; mutS (E. coli) homolog 6; MutS alpha 160kDa subunit; MutS-alpha 160kDa subunit; p160; Sperm associated protein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MSH6
Gene ID: 2956
NCBI Gene ID: 445052
UniProt: P52701
Swiss Prot: P52701
Host: Mouse
Species Reactivity: Human
Reactivity: MSH6
Immunogen: Recombinant fragment of human MSH6 protein (around aa 374-540) (exact sequence is proprietary)
Target Antigen: MSH6
Clonality: Monoclonal
Clone: MSH6/2927
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: A431 or HeLa cells. Colon Carcinoma
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 163 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL?

The catalog number for MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL is BNUB2927-100.

What sizes are available for MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL?

MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL in stock?

MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL?

MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL?

Estimated delivery time for MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL?

The safety data sheet for MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100414/msds/bnub2927-100.pdf.

What is MSH6 (DNA Mismatch Repair Protein) (MSH6/2927), 0.2mg/mL used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.