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Product details

Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL

Catalog number BNC402959-500

Price for BNC402959-500

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Size / count 1x 500 µL

About this product

Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC402959-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CK15; Cytokeratin 15; K1CO; Ka15; Keratin 15 basic; Keratin 15 beta; Keratin complex 1 acidic gene 15; Keratin type I cytoskeletal 15; KRT15; KRTB; KRTL15; Type I cytoskeletal 15; Type I keratin Ka15
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT15
Gene ID
3866
NCBI Gene ID
654570
UniProt
P19012
Swiss Prot
P19012
Host
Mouse
Species Reactivity
Human
Reactivity
Cytokeratin 15
Immunogen
Recombinant full-length human KRT15 protein
Target Antigen
Cytokeratin 15
Clonality
Monoclonal
Clone
KRT15/2959
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
MCF-7, A431 cells. Skin or Colon or Thymus.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
52 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2c, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL is BNC402959-500.

What sizes are available for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL?

Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL in stock?

Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL?

Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b0061270361e1095f8/msds/bnc402959-500.pdf.

What is Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2959), CF640R conjugate, 0.1mg/mL used for?

Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulg

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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