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Product details
Catalog number BNC402971-100
Price for BNC402971-100
Size / count 1x 100 µL
The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood. The MRP gene family also includes MRP2, which is alternatively designated cMOAT (for canalicular multispecific organic anion transporter) and MRP3, which are both conjugate export pumps exp- ressed predominantly in hepatocytes. MRP2 localizes exclusively to the apical membrane and is constitutively expressed at a high level in normal liver cells. Conversely, MRP3 localizes to the basolateral membrane where it also medi- ates the transport of the organic anion S- (2, 4-dinitrophenyl-) glutathione toward the basolateral side of the membrane. MRP3 is normally expressed at comparatively lower levels than MRP2 and increases only when secretion across the apical membrane by MRP2 is impaired. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MRP3 (Multidrug Resistance-Associated Protein 3) (ABCC3/2971), CF640R conjugate, 0.1mg/mL is BNC402971-100.
MRP3 (Multidrug Resistance-Associated Protein 3) (ABCC3/2971), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
MRP3 (Multidrug Resistance-Associated Protein 3) (ABCC3/2971), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MRP3 (Multidrug Resistance-Associated Protein 3) (ABCC3/2971), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for MRP3 (Multidrug Resistance-Associated Protein 3) (ABCC3/2971), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MRP3 (Multidrug Resistance-Associated Protein 3) (ABCC3/2971), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a0061270361e103908/msds/bnc402971-100.pdf.
The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cyt
Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.
Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
