MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL

Catalog number BNC472980-100

Price for BNC472980-100

Size / count 1x 100 µL

About this product

This MAb recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this MAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (200 kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the MAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This MAb reacts with both normal and malignant epithelia of various tissues including breast and colon. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472980-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Breast carcinoma-associated antigen DF3; CA15-3; Carcinoma-associated mucin Episialin; Epithelial Membrane Antigen; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; Mucin 1 cell surface associated; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor-associated epithelial membrane antigen
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MUC1
Gene ID: 4582
NCBI Gene ID: 89603
UniProt: P15941
Swiss Prot: P15941
Host: Rabbit
Species Reactivity: Human
Reactivity: CA15-3|CD227|EMA|MUC1
Immunogen: Recombinant full-length human MUC1 protein
Target Antigen: CA15-3 | CD227 | EMA | MUC1
Clonality: Recombinant Monoclonal
Clone: MUC1/2980R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Mucins
Positive Control: MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 265-400 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL?

The catalog number for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is BNC472980-100.

What sizes are available for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL in stock?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a4061270361e105415/msds/bnc472980-100.pdf.

What is MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL used for?

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.