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Product details

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL

Catalog number BNC472980-500

Price for BNC472980-500

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Size / count 1x 500 µL

About this product

This MAb recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this MAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (200 kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the MAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This MAb reacts with both normal and malignant epithelia of various tissues including breast and colon. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC472980-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Breast carcinoma-associated antigen DF3; CA15-3; Carcinoma-associated mucin Episialin; Epithelial Membrane Antigen; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; Mucin 1 cell surface associated; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor-associated epithelial membrane antigen
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MUC1
Gene ID
4582
NCBI Gene ID
89603
UniProt
P15941
Swiss Prot
P15941
Host
Rabbit
Species Reactivity
Human
Reactivity
CA15-3|CD227|EMA|MUC1
Immunogen
Recombinant full-length human MUC1 protein
Target Antigen
CA15-3 | CD227 | EMA | MUC1
Clonality
Recombinant Monoclonal
Clone
MUC1/2980R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Mucins
Positive Control
MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
265-400 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL?

The catalog number for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is BNC472980-500.

What sizes are available for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL in stock?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b5061270361e10af18/msds/bnc472980-500.pdf.

What is MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL used for?

This MAb recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this MAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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