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Product details

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL

Catalog number BNC942982-500

Price for BNC942982-500

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Size / count 1x 500 µL

About this product

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR) . Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH) . GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC942982-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
GnRH receptor; GnRH-R; GNRHR1; gonadotropin-releasing hormone (type 1) receptor 1; GRHR; HH7; leutinizing-releasing hormone receptor; LHRHR; LRHR; luliberin receptor; luteinizing hormone releasing hormone receptor; Type I GnRH receptor
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
GNRHR and LHCGR
Gene ID
2798; 3973
NCBI Gene ID
407587 468490
UniProt
P30968; P22888
Swiss Prot
P30968; P22888
Host
Rabbit
Species Reactivity
Human
Reactivity
GnRH Receptor|LH-RH Receptor
Immunogen
Recombinant full-length human GNRHR protein
Target Antigen
GnRH Receptor | LH-RH Receptor
Clonality
Recombinant Monoclonal
Clone
GNRHR/2982R
Type
Primary
Source
Animal
Origin
Animal
Positive Control
T47D cells. Pituitary gland, ovarian or breast cancers.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
54-60 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL?

The catalog number for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL is BNC942982-500.

What sizes are available for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL?

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL in stock?

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL?

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL?

The safety data sheet for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e1003c8/msds/bnc942982-500.pdf.

What is GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF594 conjugate, 0.1mg/mL used for?

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR) . Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonado

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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