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Product details

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2982-500

Price for BNCB2982-500

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Size / count 1x 500 µL

About this product

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR) . Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH) . GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2982-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
GnRH receptor; GnRH-R; GNRHR1; gonadotropin-releasing hormone (type 1) receptor 1; GRHR; HH7; leutinizing-releasing hormone receptor; LHRHR; LRHR; luliberin receptor; luteinizing hormone releasing hormone receptor; Type I GnRH receptor
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
GNRHR and LHCGR
Gene ID
2798; 3973
NCBI Gene ID
407587 468490
UniProt
P30968; P22888
Swiss Prot
P30968; P22888
Host
Rabbit
Species Reactivity
Human
Reactivity
GnRH Receptor|LH-RH Receptor
Immunogen
Recombinant full-length human GNRHR protein
Target Antigen
GnRH Receptor | LH-RH Receptor
Clonality
Recombinant Monoclonal
Clone
GNRHR/2982R
Type
Primary
Source
Animal
Origin
Animal
Positive Control
T47D cells. Pituitary gland, ovarian or breast cancers.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
54-60 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL?

The catalog number for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL is BNCB2982-500.

What sizes are available for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL?

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL in stock?

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL?

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101ce1/msds/bncb2982-500.pdf.

What is GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), Biotin conjugate, 0.1mg/mL used for?

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR) . Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonado

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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