BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL

Catalog number BNC042985-100

Price for BNC042985-100

Size / count 1x 100 µL

About this product

BRCA1 is a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. It combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC) . BRCA1 associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042985-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BRCA1; Breast and ovarian cancer susceptibility protein 1; Early Onset Breast Cancer 1; Protein phosphatase 1 regulatory subunit 53; RING finger protein 53
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: BRCA1
Gene ID: 672
NCBI Gene ID: 194143
UniProt: P38398
Swiss Prot: P38398
Host: Mouse
Species Reactivity: Human
Reactivity: BRCA1
Immunogen: Recombinant fragment (around aa 445-620) of human BRCA1 protein (exact sequence is proprietary)
Target Antigen: BRCA1
Clonality: Monoclonal
Clone: BRCA1/2985
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Cancer
Positive Control: A431 or HeLa Cells. Breast, Ovarian or Renal Cell Carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 220 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL?

The catalog number for BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL is BNC042985-100.

What sizes are available for BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL?

BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL in stock?

BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL?

BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL?

The safety data sheet for BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a1061270361e1042f6/msds/bnc042985-100.pdf.

What is BRCA1 (Breast Marker) (BRCA1/2985), CF405S conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.