MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL

Catalog number BNC472992-100

Price for BNC472992-100

Size / count 1x 100 µL

About this product

Recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3) . Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. MUC3 is distributed in colon and rectum, and is also present to a lesser extent in breast, lung and salivary gland tissues. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3) . The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472992-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Intestinal mucin-3A; intestinal mucin-like; MUC3; MUC3A; MUC3B; mucin 3; intestinal; mucin 3A; cell surface associated; mucin 3A; intestinal; mucin 3B; cell surface associated
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MUC3A
Gene ID: 4584 & 57876
NCBI Gene ID: 744422 & 744530
UniProt: Q02505; Q9H195
Swiss Prot: Q02505 & Q9H195
Host: Rabbit
Species Reactivity: Human
Reactivity: MUC3
Immunogen: A synthetic peptide of 35 amino acids, SIB35 (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS), which contains two of the MUC3 tandem repeats, coupled to KLH.
Target Antigen: MUC3
Clonality: Recombinant Monoclonal
Clone: MUC3/2992R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Mucins
Positive Control: LS174T cells. Human small intestine (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 1100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL?

The catalog number for MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL is BNC472992-100.

What sizes are available for MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL?

MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL in stock?

MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL?

MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e105020/msds/bnc472992-100.pdf.

What is MUC3 (Mucin 3) (MUC3/2992R), CF647 conjugate, 0.1mg/mL used for?

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.