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Product details

MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL

Catalog number BNC472999-100

Price for BNC472999-100

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Size / count 1x 100 µL

About this product

The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC472999-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
DNA replication licensing factor MCM6; MCM6 minichromosome maintenance deficient 6; MIS5 homolog; p105MCM
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MCM6
Gene ID
4175
NCBI Gene ID
444118
UniProt
Q14566
Swiss Prot
Q14566
Host
Mouse
Species Reactivity
Human
Reactivity
MCM6
Immunogen
Recombinant fragment (around aa 228-368) of human MCM6 protein (exact sequence is proprietary)
Target Antigen
MCM6
Clonality
Monoclonal
Clone
MCM6/2999
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human skin or squamous cell carcinoma (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
105 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL?

The catalog number for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is BNC472999-100.

What sizes are available for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL?

MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL in stock?

MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL?

MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b5061270361e10b2a5/msds/bnc472999-100.pdf.

What is MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL used for?

The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peak

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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