MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL

Catalog number BNC472999-500

Price for BNC472999-500

Size / count 1x 500 µL

About this product

The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472999-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: DNA replication licensing factor MCM6; MCM6 minichromosome maintenance deficient 6; MIS5 homolog; p105MCM
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MCM6
Gene ID: 4175
NCBI Gene ID: 444118
UniProt: Q14566
Swiss Prot: Q14566
Host: Mouse
Species Reactivity: Human
Reactivity: MCM6
Immunogen: Recombinant fragment (around aa 228-368) of human MCM6 protein (exact sequence is proprietary)
Target Antigen: MCM6
Clonality: Monoclonal
Clone: MCM6/2999
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human skin or squamous cell carcinoma (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 105 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL?

The catalog number for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is BNC472999-500.

What sizes are available for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL?

MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL in stock?

MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL?

MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a7061270361e10612d/msds/bnc472999-500.pdf.

What is MCM6 (Proliferation Marker) (MCM6/2999), CF647 conjugate, 0.1mg/mL used for?

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.