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Product details

MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL

Catalog number BNC403000-500

Price for BNC403000-500

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Size / count 1x 500 µL

About this product

The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC403000-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
DNA replication licensing factor MCM6; MCM6 minichromosome maintenance deficient 6; MIS5 homolog; p105MCM
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MCM6
Gene ID
4175
NCBI Gene ID
444118
UniProt
Q14566
Swiss Prot
Q14566
Host
Mouse
Species Reactivity
Human
Reactivity
MCM6
Immunogen
Recombinant fragment (around aa 228-368) of human MCM6 protein (exact sequence is proprietary)
Target Antigen
MCM6
Clonality
Monoclonal
Clone
MCM6/3000
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human skin or squamous cell carcinoma (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
105 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL?

The catalog number for MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL is BNC403000-500.

What sizes are available for MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL?

MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL in stock?

MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL?

MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL?

The safety data sheet for MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e100180/msds/bnc403000-500.pdf.

What is MCM6 (Proliferation Marker) (MCM6/3000), CF640R conjugate, 0.1mg/mL used for?

The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peak

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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