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Product details

MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL

Catalog number BNC473000-500

Price for BNC473000-500

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Size / count 1x 500 µL

About this product

The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC473000-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
DNA replication licensing factor MCM6; MCM6 minichromosome maintenance deficient 6; MIS5 homolog; p105MCM
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MCM6
Gene ID
4175
NCBI Gene ID
444118
UniProt
Q14566
Swiss Prot
Q14566
Host
Mouse
Species Reactivity
Human
Reactivity
MCM6
Immunogen
Recombinant fragment (around aa 228-368) of human MCM6 protein (exact sequence is proprietary)
Target Antigen
MCM6
Clonality
Monoclonal
Clone
MCM6/3000
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human skin or squamous cell carcinoma (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
105 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL?

The catalog number for MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL is BNC473000-500.

What sizes are available for MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL?

MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL in stock?

MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL?

MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101fbd/msds/bnc473000-500.pdf.

What is MCM6 (Proliferation Marker) (MCM6/3000), CF647 conjugate, 0.1mg/mL used for?

The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peak

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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