MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL

Catalog number BNUB3000-100

Price for BNUB3000-100

Size / count 1x 100 µL

About this product

The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB3000-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: DNA replication licensing factor MCM6; MCM6 minichromosome maintenance deficient 6; MIS5 homolog; p105MCM
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MCM6
Gene ID: 4175
NCBI Gene ID: 444118
UniProt: Q14566
Swiss Prot: Q14566
Host: Mouse
Species Reactivity: Human
Reactivity: MCM6
Immunogen: Recombinant fragment (around aa 228-368) of human MCM6 protein (exact sequence is proprietary)
Target Antigen: MCM6
Clonality: Monoclonal
Clone: MCM6/3000
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human skin or squamous cell carcinoma (IHC).
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 105 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL?

The catalog number for MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL is BNUB3000-100.

What sizes are available for MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL?

MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL in stock?

MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL?

MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL?

Estimated delivery time for MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL?

The safety data sheet for MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a4061270361e1050db/msds/bnub3000-100.pdf.

What is MCM6 (Proliferation Marker) (MCM6/3000), 0.2mg/mL used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.