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Product details

Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL

Catalog number BNUB3001-500

Price for BNUB3001-500

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Size / count 1x 500 µL

About this product

Iron (Fe) is a tightly metabolically controlled mineral and growth factor present in all living cells. Iron not bound in erythrocyte hemoglobin is transported by transferrin (Tf), the iron transport protein of vertebrate serum. The transferrin protein contains two homologous domains, each of which contain an Fe-binding site. The majority of transferrin is synthesized in the liver and secreted into the blood, but it is also produced in lower amounts in testis and brain as well as in oligodendrocytes, where transferrin is an early marker of oligodendrocyte differentiation. From the blood, transferrin is internalized by erythroblasts and reticulocytes upon binding the transferrin receptor (TfR), also designated CD71, through a system of coated pits and vesicles. After Fe release, transferrin is returned to the extracellular medium, where it can be reused. Defects in the transferrin gene results in atransferrinemia, a rare autosomal recessive disorder characterized by microcytic anemia and iron loading. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB3001-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Apotransferrin; Beta-1 metal-binding globulin; Serotransferrin; Siderophilin; TF; TFQTL1; Transferrin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TF
Gene ID
7018
NCBI Gene ID
518267
UniProt
P02787
Swiss Prot
P02787
Host
Mouse
Species Reactivity
Human
Reactivity
Transferrin
Immunogen
Recombinant fragment (around aa 311-445) of human TF protein (exact sequence is proprietary)
Target Antigen
Transferrin
Clonality
Monoclonal
Clone
TF/3001
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Jurkat, HeLa, MCF-7 or K562 cells. Human liver.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
79 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL?

The catalog number for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL is BNUB3001-500.

What sizes are available for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL?

Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL in stock?

Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL?

Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL?

Estimated delivery time for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL?

The safety data sheet for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101ec3/msds/bnub3001-500.pdf.

What is Transferrin (Early Marker of Oligodendrocytes) (TF/3001), 0.2mg/mL used for?

Iron (Fe) is a tightly metabolically controlled mineral and growth factor present in all living cells. Iron not bound in erythrocyte hemoglobin is transported by transferrin (Tf), the iron transport protein of vertebrate serum. The transferrin protein contains two homologous domains, each of which c

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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