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Product details
Catalog number BNUM3025-50
Price for BNUM3025-50
Size / count 1x 50 µL
LSP1 is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific (including B and T lymphocytes, granulocytes and macrophages), phosphoprotein. However, mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell lines as well (myocytes, stromal cells and fibroblasts), suggesting pp52 has a divergent role in signal transduction. The pp52 (LSP1) locus maps to human chromosome 11p15. 5, which is implicated in tumor-related chromosomal translocations found in chronic lymphocytic leukemia. The pp52 promoter contains key elements that control transcriptional activity including an initiator specifying the unique 5' terminus of pp52 mRNA, tandem pairs of Ets and SP1 motifs, and a single C/EBP motif. LSP1 binds the cytoskeleton and has been implicated in affecting cytoskeletal remodeling in a variety of leukocyte functions, including cell motility and chemotaxis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Lymphocyte Specific Protein 1 (LSP1) / pp52 (LSP1/3025), 1mg/mL is BNUM3025-50.
Lymphocyte Specific Protein 1 (LSP1) / pp52 (LSP1/3025), 1mg/mL is available in the following size(s): 1x 50 µL.
Lymphocyte Specific Protein 1 (LSP1) / pp52 (LSP1/3025), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Lymphocyte Specific Protein 1 (LSP1) / pp52 (LSP1/3025), 1mg/mL is manufactured by Biotium.
Estimated delivery time for Lymphocyte Specific Protein 1 (LSP1) / pp52 (LSP1/3025), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Lymphocyte Specific Protein 1 (LSP1) / pp52 (LSP1/3025), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029e061270361e102f06/msds/bnum3025-50.pdf.
LSP1 is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific (including B and T lymphocytes, granulocytes and macrophages), phosphoprotein. However, mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell line
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.
Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.
