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Product details
Catalog number BNC683059-100
Price for BNC683059-100
Size / count 1x 100 µL
In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc1) . The Cdc/cyclin enzyme is subject to multiple levels of control, of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/ cyclin B enzyme, and tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex. Evidence has established that B type cyclins not only act on M phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The two B type cyclins, cyclin B1 and cyclin B2, have been shown to have distinct tissue distributions. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Cyclin B2 (X29.2), CF568 conjugate, 0.1mg/mL is BNC683059-100.
Cyclin B2 (X29.2), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Cyclin B2 (X29.2), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Cyclin B2 (X29.2), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Cyclin B2 (X29.2), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Cyclin B2 (X29.2), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a2061270361e104551/msds/bnc683059-100.pdf.
In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
