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Product details

Cyclin B2 (X29.2), 0.2mg/mL

Catalog number BNUB3059-100

Price for BNUB3059-100

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Size / count 1x 100 µL

About this product

In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc1) . The Cdc/cyclin enzyme is subject to multiple levels of control, of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/ cyclin B enzyme, and tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex. Evidence has established that B type cyclins not only act on M phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The two B type cyclins, cyclin B1 and cyclin B2, have been shown to have distinct tissue distributions. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB3059-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Ccnb2; CycB2; Cyclin B2; G2 mitotic specific cyclin B2; HsT17299; MGC108931; MGC140694
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CCNB2
Gene ID
9133
NCBI Gene ID
194698
UniProt
O95067
Swiss Prot
O95067
Host
Mouse
Species Reactivity
Human, Mouse, Rat, Xenopus
Reactivity
Cyclin B2
Immunogen
Recombinant full-length Xenopus laevis Cyclin B2 protein
Target Antigen
Cyclin B2
Clonality
Monoclonal
Clone
X29.2
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (published)
Positive Control
HeLa cells. Human cervical tissue (IHC).
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
51 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. PLoS ONE 3(4): e1871. (IF)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Cyclin B2 (X29.2), 0.2mg/mL?

The catalog number for Cyclin B2 (X29.2), 0.2mg/mL is BNUB3059-100.

What sizes are available for Cyclin B2 (X29.2), 0.2mg/mL?

Cyclin B2 (X29.2), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Cyclin B2 (X29.2), 0.2mg/mL in stock?

Cyclin B2 (X29.2), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cyclin B2 (X29.2), 0.2mg/mL?

Cyclin B2 (X29.2), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cyclin B2 (X29.2), 0.2mg/mL?

Estimated delivery time for Cyclin B2 (X29.2), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cyclin B2 (X29.2), 0.2mg/mL?

The safety data sheet for Cyclin B2 (X29.2), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e0ffe4a/msds/bnub3059-100.pdf.

What is Cyclin B2 (X29.2), 0.2mg/mL used for?

In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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