HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL

Catalog number BNC043066-100

Price for BNC043066-100

Size / count 1x 100 µL

About this product

The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16, a 'high-risk' sexually-transmitted HPV that can lead to cervical, anal, vulvar, head, neck, and penile cancer. The HPV16E1/E4 protein is expressed abundantly in cells supporting viral DNA amplification, but is lost during malignant progression. HPV16E1/E4 causes G2 cell cycle arrest by associating with and preventing the nuclear entry of Cdk1/cyclin B1 complexes. HPV16E1/E4 also interacts with cyclin A and Cdk2 during the G2 phase of the cell cycle, and this association may increase the efficiency with which HPV16E1/E4 is able to prevent mitotic entry. HPV16E1/E4 also associates with keratin intermediate filaments and causes the network to collapse. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC043066-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: HPV-16; HPV-16 capsid; HPV16 L1; HPV16 major capsid protein L1; Human papillomavirus type 16 L1; Human papillomavirus type 16 major capsid protein L1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: Not Applicable
UniProt: Not Applicable
Swiss Prot: Not Applicable
Host: Mouse
Species Reactivity: HPV-16
Reactivity: E4|HPV16 E1
Immunogen: Recombinant human HPV16 E1/E4 fragment (aa 36-41) .
Target Antigen: E4 | HPV16 E1
Clonality: Monoclonal
Clone: HPV16 E1/E4
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: HPV-16 infected cells. Cervical tissue.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 16 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL?

The catalog number for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is BNC043066-100.

What sizes are available for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL?

HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL in stock?

HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL?

HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL?

The safety data sheet for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a0061270361e103949/msds/bnc043066-100.pdf.

What is HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.