Product details
Catalog number BNC043066-500
Price for BNC043066-500
Size / count 1x 500 µL
The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16, a 'high-risk' sexually-transmitted HPV that can lead to cervical, anal, vulvar, head, neck, and penile cancer. The HPV16E1/E4 protein is expressed abundantly in cells supporting viral DNA amplification, but is lost during malignant progression. HPV16E1/E4 causes G2 cell cycle arrest by associating with and preventing the nuclear entry of Cdk1/cyclin B1 complexes. HPV16E1/E4 also interacts with cyclin A and Cdk2 during the G2 phase of the cell cycle, and this association may increase the efficiency with which HPV16E1/E4 is able to prevent mitotic entry. HPV16E1/E4 also associates with keratin intermediate filaments and causes the network to collapse. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is BNC043066-500.
HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a7061270361e10634c/msds/bnc043066-500.pdf.
The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16, a 'high-risk' sexually-transmitted HPV that can lead to cervical, anal, vulvar, head, neck, and penile cancer. The HPV16E1/E4 protein is expressed abundantly in cells supporting viral DNA amplification, but is lost during ma
Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.
If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.
Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.