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Product details
Catalog number BNC403067-500
Price for BNC403067-500
Size / count 1x 500 µL
The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation. Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins. ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors. Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis. ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin. ORC4 and ORC6 are also expressed constantly throughout the cell cycle. ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble. The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for ORC1 (7F6/1), CF640R conjugate, 0.1mg/mL is BNC403067-500.
ORC1 (7F6/1), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
ORC1 (7F6/1), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
ORC1 (7F6/1), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for ORC1 (7F6/1), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for ORC1 (7F6/1), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a4061270361e1053a5/msds/bnc403067-500.pdf.
The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation. Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins. ORC proteins bind specifically to origins of
Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.
A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.
Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.
