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Product details

Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL

Catalog number BNC043068-500

Price for BNC043068-500

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Size / count 1x 500 µL

About this product

Recognizes a protein of ~150 kDa, identified as Desmoglein-1 (DSG1) . Desmoglein-1 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC043068-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cadherin family member 4; CDHF4; Desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG1; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
DSG1
Gene ID
1828
NCBI Gene ID
2633
UniProt
Q02413
Swiss Prot
Q02413
Host
Mouse
Species Reactivity
Human
Reactivity
Desmoglein-1
Immunogen
Bovine desmoglein (desmosomal glyco protein I) from nasal epidermis.
Target Antigen
Desmoglein-1
Clonality
Monoclonal
Clone
32-2B
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Bladder, skin or melanoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
150 kDa (precursor) ; 160 kDa (mature)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL?

The catalog number for Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL is BNC043068-500.

What sizes are available for Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL?

Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL in stock?

Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL?

Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b9061270361e10c6df/msds/bnc043068-500.pdf.

What is Desmoglein-1 (DSG1) (32-2B), CF405S conjugate, 0.1mg/mL used for?

Recognizes a protein of ~150 kDa, identified as Desmoglein-1 (DSG1) . Desmoglein-1 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosom

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

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