Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL

Catalog number BNC473068-100

Price for BNC473068-100

Size / count 1x 100 µL

About this product

Recognizes a protein of ~150 kDa, identified as Desmoglein-1 (DSG1) . Desmoglein-1 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC473068-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cadherin family member 4; CDHF4; Desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG1; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: DSG1
Gene ID: 1828
NCBI Gene ID: 2633
UniProt: Q02413
Swiss Prot: Q02413
Host: Mouse
Species Reactivity: Human
Reactivity: Desmoglein-1
Immunogen: Bovine desmoglein (desmosomal glyco protein I) from nasal epidermis.
Target Antigen: Desmoglein-1
Clonality: Monoclonal
Clone: 32-2B
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Bladder, skin or melanoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 150 kDa (precursor) ; 160 kDa (mature)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL?

The catalog number for Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL is BNC473068-100.

What sizes are available for Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL?

Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL in stock?

Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL?

Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02aa061270361e107450/msds/bnc473068-100.pdf.

What is Desmoglein-1 (DSG1) (32-2B), CF647 conjugate, 0.1mg/mL used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.