• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL

Catalog number BNC043070-500

Price for BNC043070-500

Sign In for Pricing

Size / count 1x 500 µL

About this product

The AAA protein family members share an ATPase domain and have roles in various cellular processes including intracellular motility, membrane trafficking, proteolysis, protein folding and organelle biogenesis. Spastin, a member of the AAA protein family, is a 616 amino acid protein and is involved in the function or assembly of nuclear protein complexes. The Spastin protein is expressed ubiquitously and localizes to the nucleus and the cytoplasm, where it may also be involved in microtubule dynamics. Mutations in the Spastin gene (SPAST, SPG4) cause the most common form of spastic paraplegia 4, an autosomal dominant form of hereditary spastic paraplegia (HSP) . HSPs comprise a group of inherited neurological disorders characterized by spastic lower extremity weakness due to a length-dependent, retrograde axonopathy of corticospinal motor neurons. SPAST-specific mutations account for approximately 40% of all autosomal dominant HSPs. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC043070-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ADPSP; FSP2; Spast; Spatin; SPG4
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SPAST
Gene ID
6683
NCBI Gene ID
468091
UniProt
Q9UP0
Swiss Prot
Q9UP0
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
Spastin
Immunogen
Recombinant full-length human Spastin protein.
Target Antigen
Spastin
Clonality
Monoclonal
Clone
Sp 6C6
Type
Primary
Source
Animal
Origin
Animal
Applications
WB (verified)
Positive Control
HeLa cells. K-562 or Raji cell lysates.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
52 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL?

The catalog number for Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL is BNC043070-500.

What sizes are available for Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL?

Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL in stock?

Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL?

Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e1000df/msds/bnc043070-500.pdf.

What is Spastin (Sp 6C6), CF405S conjugate, 0.1mg/mL used for?

The AAA protein family members share an ATPase domain and have roles in various cellular processes including intracellular motility, membrane trafficking, proteolysis, protein folding and organelle biogenesis. Spastin, a member of the AAA protein family, is a 616 amino acid protein and is involved i

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

You Might Also Like
CD3e (CRIS-7), CF647 conjugate, 0.1mg/mL
CD3e (CRIS-7), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471050-100
Cytokeratin 8/18 (C-51), CF568 conjugate, 0.1mg/mL
Cytokeratin 8/18 (C-51), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680034-500
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880225-500
Complement C4d (C4D204), CF568 conjugate, 0.1mg/mL
Complement C4d (C4D204), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680204-100
P27 / KIP1 (SX53G8), CF405S conjugate, 0.1mg/mL
P27 / KIP1 (SX53G8), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040669-500
CD71 (66IG10), CF647 conjugate, 0.1mg/mL
CD71 (66IG10), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470871-500
Cytokeratin, LMW (AE-1), CF647 conjugate, 0.1mg/mL
Cytokeratin, LMW (AE-1), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470253-500
CD47 (B6H12.2), CF740 conjugate, 0.1mg/mL
CD47 (B6H12.2), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740437-100