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Product details

Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL

Catalog number BNC403070-100

Price for BNC403070-100

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Size / count 1x 100 µL

About this product

The AAA protein family members share an ATPase domain and have roles in various cellular processes including intracellular motility, membrane trafficking, proteolysis, protein folding and organelle biogenesis. Spastin, a member of the AAA protein family, is a 616 amino acid protein and is involved in the function or assembly of nuclear protein complexes. The Spastin protein is expressed ubiquitously and localizes to the nucleus and the cytoplasm, where it may also be involved in microtubule dynamics. Mutations in the Spastin gene (SPAST, SPG4) cause the most common form of spastic paraplegia 4, an autosomal dominant form of hereditary spastic paraplegia (HSP) . HSPs comprise a group of inherited neurological disorders characterized by spastic lower extremity weakness due to a length-dependent, retrograde axonopathy of corticospinal motor neurons. SPAST-specific mutations account for approximately 40% of all autosomal dominant HSPs. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC403070-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ADPSP; FSP2; Spast; Spatin; SPG4
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SPAST
Gene ID
6683
NCBI Gene ID
468091
UniProt
Q9UP0
Swiss Prot
Q9UP0
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
Spastin
Immunogen
Recombinant full-length human Spastin protein.
Target Antigen
Spastin
Clonality
Monoclonal
Clone
Sp 6C6
Type
Primary
Source
Animal
Origin
Animal
Applications
WB (verified)
Positive Control
HeLa cells. K-562 or Raji cell lysates.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
52 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL?

The catalog number for Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL is BNC403070-100.

What sizes are available for Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL?

Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL in stock?

Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL?

Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029e061270361e10316b/msds/bnc403070-100.pdf.

What is Spastin (Sp 6C6), CF640R conjugate, 0.1mg/mL used for?

The AAA protein family members share an ATPase domain and have roles in various cellular processes including intracellular motility, membrane trafficking, proteolysis, protein folding and organelle biogenesis. Spastin, a member of the AAA protein family, is a 616 amino acid protein and is involved i

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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