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Product details

Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL

Catalog number BNC683070-100

Price for BNC683070-100

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Size / count 1x 100 µL

About this product

The AAA protein family members share an ATPase domain and have roles in various cellular processes including intracellular motility, membrane trafficking, proteolysis, protein folding and organelle biogenesis. Spastin, a member of the AAA protein family, is a 616 amino acid protein and is involved in the function or assembly of nuclear protein complexes. The Spastin protein is expressed ubiquitously and localizes to the nucleus and the cytoplasm, where it may also be involved in microtubule dynamics. Mutations in the Spastin gene (SPAST, SPG4) cause the most common form of spastic paraplegia 4, an autosomal dominant form of hereditary spastic paraplegia (HSP) . HSPs comprise a group of inherited neurological disorders characterized by spastic lower extremity weakness due to a length-dependent, retrograde axonopathy of corticospinal motor neurons. SPAST-specific mutations account for approximately 40% of all autosomal dominant HSPs. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC683070-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ADPSP; FSP2; Spast; Spatin; SPG4
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SPAST
Gene ID
6683
NCBI Gene ID
468091
UniProt
Q9UP0
Swiss Prot
Q9UP0
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
Spastin
Immunogen
Recombinant full-length human Spastin protein.
Target Antigen
Spastin
Clonality
Monoclonal
Clone
Sp 6C6
Type
Primary
Source
Animal
Origin
Animal
Applications
WB (verified)
Positive Control
HeLa cells. K-562 or Raji cell lysates.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
52 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL?

The catalog number for Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL is BNC683070-100.

What sizes are available for Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL?

Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL in stock?

Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL?

Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a1061270361e1041bd/msds/bnc683070-100.pdf.

What is Spastin (Sp 6C6), CF568 conjugate, 0.1mg/mL used for?

The AAA protein family members share an ATPase domain and have roles in various cellular processes including intracellular motility, membrane trafficking, proteolysis, protein folding and organelle biogenesis. Spastin, a member of the AAA protein family, is a 616 amino acid protein and is involved i

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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