- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
Select the image to view it full size.
Product details
Catalog number BNCB3070-100
Price for BNCB3070-100
Size / count 1x 100 µL
The AAA protein family members share an ATPase domain and have roles in various cellular processes including intracellular motility, membrane trafficking, proteolysis, protein folding and organelle biogenesis. Spastin, a member of the AAA protein family, is a 616 amino acid protein and is involved in the function or assembly of nuclear protein complexes. The Spastin protein is expressed ubiquitously and localizes to the nucleus and the cytoplasm, where it may also be involved in microtubule dynamics. Mutations in the Spastin gene (SPAST, SPG4) cause the most common form of spastic paraplegia 4, an autosomal dominant form of hereditary spastic paraplegia (HSP) . HSPs comprise a group of inherited neurological disorders characterized by spastic lower extremity weakness due to a length-dependent, retrograde axonopathy of corticospinal motor neurons. SPAST-specific mutations account for approximately 40% of all autosomal dominant HSPs. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Spastin (Sp 6C6), Biotin conjugate, 0.1mg/mL is BNCB3070-100.
Spastin (Sp 6C6), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Spastin (Sp 6C6), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Spastin (Sp 6C6), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Spastin (Sp 6C6), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Spastin (Sp 6C6), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e104e6e/msds/bncb3070-100.pdf.
The AAA protein family members share an ATPase domain and have roles in various cellular processes including intracellular motility, membrane trafficking, proteolysis, protein folding and organelle biogenesis. Spastin, a member of the AAA protein family, is a 616 amino acid protein and is involved i
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.
Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.
Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.
